IV iron:
- Should be reserved as a second line treatment choice in the management of IDA.*
- Does not produce a faster Hb response than oral iron (provided that the oral iron preparation is taken reliably and is absorbed adequately).
- Can cause hypersensitivity reactions which may be life-threatening or fatal (only administer during working hours when adequate supervision is available).
- Paravenous leakage may lead to permanent staining at the site of infusion.
* see inclusion criteria for IV iron therapy in full guideline, including use as first line agent in certain clinical settings.