7.2. Treatment of vaginal and vulval conditions
7.2.1. Preparations for vaginal and vulval changes
Ovestin cream contains 1mg estriol in 1g of cream (0.1%)
The estriol concentration of estriol intravaginal cream is 0.01%. This preparation contains arachis (peanut) oil and is not suitable for patient with peanut allergy. This preparation also damages latex condoms. Ovestin intravaginal cream is 0.1% and does not contain arachis oil.
Treatment of moderate to severe symptomatic vulvar and vaginal atrophy (VVA) in post-menopausal women who are not candidates for local vaginal oestrogen therapy is restricted to intitiation by, or on advice of, a specialist.
7.2.2. Vaginal and vulval infections
One pessary contains 500mg of clotrimazole.
the clotrimazole content is 1%.
The treatment of bacterial vaginosis is restricted to use in patients for whom the initial treatment is not effective or well tolerated.
Metronidazole gel is restricted to patients unable to tolerate or comply with oral metronidazole therapy.
7.2.3. Preparations for uterine fibroids
Restricted to specialist initiation for use in patients who have failed or are unsuitable for conventional therapies (first line treatments), such as tranexamic acid, hormonal contraceptives and intrauterine delivery systems.
The treatment of moderate to severe symptoms of uterine fibroids in adult women is restricted to the following MHRA advice:
- intermittent treatment of moderate to severe symptoms of uterine fibroids in women of reproductive age who are not eligible for surgery or where surgery has failed
- treatment is to be initiated and supervised by a physician experienced in the diagnosis and treatment of uterine fibroids
Please refer to MHRA information prior to initiation.