Greater Glasgow and Clyde Medicines

Latest Medicines Updates & News

Metformin and reduced vitamin B12 levels

Posted: Monday, November 14, 2022

Category - Medicines Update

  • Metformin can commonly reduce vitamin B12 levels in patients, which may lead to vitamin B12 deficiency. Refer to MHRA Drug Safety Update here.

  • B12 deficiency risk increases with higher metformin doses, longer treatment duration and patients with a risk of B12 deficiency (see below for additional risk factors)

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Menopause information and prescribing resources

Posted: Monday, October 31, 2022

Category - Medicines Update

Key messages

  • Refer to available guidance for information on how to alleviate symptoms of the menopause (see links in further information below)
  • Refer to the NHSGGC Adult Medicines Formulary for preferred hormone replacement therapy (HRT) options
  • If ‘off-label’ testosterone is being considered for low sexual desire (when HRT alone is not effective), refer to NICE and British Menopause Society (BMS) guidance and the NHSGGC Unlicensed Medicines Policy
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