Greater Glasgow and Clyde Medicines
Key to symbols The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP The medicine should only be used and prescribed by a specialist Indicates the preferred choice within a class or group of medicines
The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP
The medicine should only be used and prescribed by a specialist
Indicates the preferred choice within a class or group of medicines
2. Cardiovascular system

2.2. Diuretics

2.2.1. Thiazides and related diuretics

The choice of therapeutic class for the management of hypertension is dependent on individual patient parameters. See the NHSGGC Guidelines for the Management of Hypertension, available on the Clinical Guidelines store on StaffNet - see link in Navigation Panel.
Preferred List
BENDROFLUMETHIAZIDE
Total Formulary
Specialist and GP
METOLAZONE

Restrictions: Restricted to specialist initiation.

BNF Link

2.2.2. Loop diuretics

Preferred List
FUROSEMIDE
Total Formulary
BUMETANIDE

2.2.3. Potassium-sparing diuretics and aldosterone antagonists

Preferred List
SPIRONOLACTONE

Prescribing Notes:

Used in heart failure and in Conn’s syndrome or decompensated liver diseases (ascites). Combination with ACE inhibitors, angiotensin-II receptor antagonists (AIIRAs) or potassium supplements may result in hyperkalaemia (monitor).

 

Near Patient Testing (NPT) arrangements for GPs may be in place for this medicine.  See the relevant section in the Prescribing Resources page for current information.

BNF Link

AMILORIDE
Total Formulary
Specialist and GP
EPLERENONE

Restrictions:

Please see prescribing notes below.

Prescribing Notes:

Eplerenone is currently formulary for two indications:  

  • The use in patients with left ventricular systolic dysfunction accompanied by evidence of heart failure, both manifesting within 3-14 days of myocardial infarction is restricted to specialist initiation and a consultant signature is required.
  • The use in addition to standard optimal therapy, to reduce the risk of cardiovascular mortality and morbidity in adult patients with NYHA class II (chronic) heart failure and left ventricular systolic dysfunction (LVEF ≤30%) is restricted to prescribers working with specialised heart failure teams only for use in patients intolerant to spironolactone.

Near Patient Testing (NPT) arrangements for GPs may be in place for this medicine.  See the relevant section in the Prescribing Resources page for current information.

BNF Link

2.2.4. Potassium-sparing diuretics with other diuretics

Total Formulary
CO-AMILOFRUSE

2.2.5. Osmotic diuretics

Total Formulary
Specialist Only
MANNITOL (intravenous infusion)

Restrictions: Restricted to specialist use only.

Prescribing Notes:

For inhaled mannitol for cystic fibrosis see section 3.7 Mucolytics

BNF Link

2.2.6. Mercurial diuretics

No medicines are included in this section

2.2.7. Carbonic anhydrase inhibitors

No medicines are included in this section

2.2.8. Diuretics with potassium

No medicines are included in this section