Key to symbols
The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP
The medicine should only be used and prescribed by a specialist
Indicates the preferred choice within a class or group of medicines
1. Gastro-intestinal system
1.2. Antispasmodics and other drugs altering gut motility
Other than in the early phase of irritable bowel disease, the place in therapy of antispasmodics is questionable. Reassurance, diet, fluids, exercise, bulking agents and lifestyle modifications achieve best results
Preferred List
DOMPERIDONE
Prescribing Notes:
In April 2014, following a Europe-wide review, the MHRA issued advice to healthcare professionals relating to the use of domperidone, restricting its use to relief or nausea and vomiting, advising that it should be used at the lowest effective dose for the shortest possible time, and highlighting changes to the contraindications, dosing and duration of treatment of the medicine.
The full advice from the MHRA can be accessed here.
MEBEVERINE HYDROCHLORIDE (TABLETS)
Restrictions:
Excludes modified-release preparations
Prescribing Notes:
Where possible, the tablets should be used as the oral suspension is significantly more expensive