Greater Glasgow and Clyde Medicines

Restrictions:

Restricted to specialist use for the following indications:

• The treatment of disease-related splenomegaly or symptoms in adult patients with primary myelofibrosis (also known as chronic idiopathic myelofibrosis), post polycythaemia vera myelofibrosis or post-essential thrombocythaemia myelofibrosis, in accordance with regional protocols [NHS network access required].
• The treatment of adult patients with polycythaemia vera who are resistant to or intolerant of hydroxyurea (hydroxycarbamide) in accordance with regional protocols [NHS network access required].
• Treatment of patients aged 12 years and older with acute graft versus host disease who have inadequate response to corticosteroids. 

Prescribing Notes:

The following indications are not recommended by SMC and remain non-formulary (approval via IPTR process):

• patients aged 12 years and older with chronic graft versus host disease who have inadequate response to corticosteroids
• ruxolitinib cream (Opzelura^®) for the treatment of non-segmental vitiligo with facial involvement

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