Greater Glasgow and Clyde Medicines

Restrictions:

Restricted to specialist use in accordance with regional protocol for the following indications:

• The treatment of disease-related splenomegaly or symptoms in adult patients with primary myelofibrosis (also known as chronic idiopathic myelofibrosis), post polycythaemia vera myelofibrosis or post-essential thrombocythaemia myelofibrosis (regional protocol)
• The treatment of adult patients with polycythaemia vera who are resistant to or intolerant of hydroxyurea (hydroxycarbamide). Click here for regional protocol (NHS network access required)

Prescribing Notes:

The following indications are not recommended by SMC and are non-Formulary:

• treatment of patients aged 12 years and older with acute graft versus host disease who have inadequate response to corticosteroids 
• patients aged 12 years and older with chronic graft versus host disease who have inadequate response to corticosteroids
• ruxolitinib cream (Opzelura^®) for the treatment of non-segmental vitiligo with facial involvement

BNF Link