Greater Glasgow and Clyde Medicines

Restrictions:

Restricted to specialist use for indications detailed under Prescribing Notes.

Prescribing Notes:

Formulary indications are:

• Use in adults for the treatment of neovascular (wet) age-related macular degeneration. 
• Treatment of visual impairment due to macular oedema secondary to central retinal vein occlusion in accordance with NHSGGC protocol. 
• Treatment of visual impairment due to macular oedema secondary to branch retinal vein occlusion (protocol in development)
• Treatment of visual impairment due to diabetic macular oedema (DMO) in adults.  It is restricted to specialist use for the treatment of visual impairment due to DMO in adults with best corrected visual acuity (BCVA) 75 Early Treatment Diabetic Retinopathy Study (ETDRS) letters or less at baseline. 
• Treatment of visual impairment due to myopic choroidal neovascularisation (myopic CNV) in line with national guidance.

BNF Link

Restrictions:

In combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) chemotherapy, aflibercept is indicated in adults with metastatic colorectal cancer (mCRC) that is resistant to or has progressed after an oxaliplatin containing regimen. It is restricted to specialist use in accordance with regional protocol.

Prescribing Notes:

For the relevant regional protocol please click here

BNF Link