Key to symbols
The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP
The medicine should only be used and prescribed by a specialist
Indicates the preferred choice within a class or group of medicines
7.2. Treatment of vaginal and vulval conditions
7.2.3. Preparations for uterine fibroids and endometriosis
Total Formulary
RELUGOLIX, ESTRADIOL AND NORETHISTERONE (RYEQO) (tablets)
Restrictions:
Restricted to specialist initiation according to GGC protocols:
- for treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age who have failed or are unsuitable for conventional therapies (first line treatments), such as tranexamic acid, hormonal contraceptives and intrauterine delivery systems.
- for symptomatic treatment of endometriosis in adult women of reproductive age with a history of previous medical or surgical treatment for their endometriosis.
ULIPRISTAL ACETATE (ESMYA) (tablets)
Restrictions:
The treatment of moderate to severe symptoms of uterine fibroids in adult women is restricted to the following MHRA advice:
- intermittent treatment of moderate to severe symptoms of uterine fibroids in women of reproductive age who are not eligible for surgery or where surgery has failed
- treatment is to be initiated and supervised by a physician experienced in the diagnosis and treatment of uterine fibroids
Please refer to MHRA information prior to initiation.