7.2. Treatment of vaginal and vulval conditions
7.2.3. Preparations for uterine fibroids
Total Formulary
![Specialist and GP](/media/nvqdugoe/specialist-gp.png)
RELUGOLIX, ESTRADIOL AND NORETHISTERONE (RYEQO) (tablets)
Restrictions:
Restricted to specialist initiation for use in patients who have failed or are unsuitable for conventional therapies (first line treatments), such as tranexamic acid, hormonal contraceptives and intrauterine delivery systems.
![Specialist and GP](/media/nvqdugoe/specialist-gp.png)
ULIPRISTAL ACETATE (ESMYA) (tablets)
Restrictions:
The treatment of moderate to severe symptoms of uterine fibroids in adult women is restricted to the following MHRA advice:
- intermittent treatment of moderate to severe symptoms of uterine fibroids in women of reproductive age who are not eligible for surgery or where surgery has failed
- treatment is to be initiated and supervised by a physician experienced in the diagnosis and treatment of uterine fibroids
Please refer to MHRA information prior to initiation.