10.2. Drugs used in neuromuscular disorders
10.2.1. Drugs that enhance neuromuscular transmission

Restrictions: Restricted to specialist initiation.
Prescribing Notes:
This medication is used for myasthenia gravis.
10.2.2. Skeletal muscle relaxants
Prescribing Notes:
Available as quinine sulphate and quinine bisulphate tablets, oral quinine is used primarily for nocturnal leg cramps. Patients should be reviewed regularly to establish benefit.
Restrictions: Baclofen injection is restricted to use in specialist units only. Slow withdrawal of baclofen over one to two weeks is recommended.

Restrictions: Restricted to specialist initiation. Restricted to recommendation by designated specialists.
10.2.3. Other neuromuscular drugs

Restrictions:
Restricted to specialist use only for the treatment of type II and III 5q spinal muscular atrophy (SMA).
Prescribing Notes:
- Formulary status will be reconsidered following the reassessment by SMC (expected July 2022).
- SMA type I is already accepted for use by SMC and is available in the GGC Paediatric Formulary.

Restrictions:
Restricted to specialist use for the symptomatic treatment of myotonia in adults with non-dystrophic myotonic disorders.