Greater Glasgow and Clyde Medicines
Key to symbols The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP The medicine should only be used and prescribed by a specialist Indicates the preferred choice within a class or group of medicines
The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP
The medicine should only be used and prescribed by a specialist
Indicates the preferred choice within a class or group of medicines
6. Endocrine system

6.4. Sex hormones

6.4.1. Female sex hormones

6.4.1.1. Oestrogens and HRT

Preferred List
Preferred List First Line
ELLESTE SOLO

Prescribing Notes:

Contains estradiol 1mg.

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TIBOLONE

Prescribing Notes:

Used for the short-term treatment of symptoms of oestrogen deficiency, tibolone is not suitable for use in the pre-menopausal stage or within 12 months of the last menstrual period (unless being treated with gonadotrophin releasing hormone analogues).

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EVOREL CONTI

Prescribing Notes:

Estradiol and norethisterone acetate.

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FEMOSTON CONTI

Prescribing Notes:

Estradiol and dydrogesterone.

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ELLESTE - DUET CONTI

Prescribing Notes:

Estradiol and norethisterone acetate.

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KLIOVANCE

Prescribing Notes:

Estradiol and norethisterone acetate.

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EVOREL SEQUI

Prescribing Notes:

Combination of Evorel® 50 patches (containing estradiol) and Evorel® Conti patches (estradiol and norethisterone acetate).

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FEMOSTON

Prescribing Notes:

Available as 1/10 and 2/10 strengths. Contains estradiol and dydrogesterone.

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ELLESTE - DUET

Prescribing Notes:

Available as estradiol 1mg or 2mg with norethisterone 1mg.

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EVOREL

Prescribing Notes:

Transdermal patch containing estradiol. Available in 25, 50, 75 and 100 micrograms/24hour strengths.

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Total Formulary
SEE BNF

Restrictions: The following HRT preparations are non-formulary: Angeliq®

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Specialist and GP
RALOXIFENE HYDROCHLORIDE

Restrictions: Restricted to specialist initiation. Restricted to use in patients for whom bisphosphonates are contraindicated or not appropriate.

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ESTRADIOL (OESTROGEL) (GEL)

Restrictions: Restricted to patients who fail to tolerate oral or patch preparations.

Prescribing Notes:

Strength: 0.6%

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ESTRADIOL (ESTRADOT) (PATCH)

6.4.1.2. Progestogens

Preferred List
DYDROGESTERONE
NORETHISTERONE
Total Formulary
Specialist and GP
ULIPRISTAL ACETATE (ESMYA) (tablets)

Restrictions:

The treatment of moderate to severe symptoms of uterine fibroids in adult women is restricted to the following MHRA advice:

  • intermittent treatment of moderate to severe symptoms of uterine fibroids in women of reproductive age who are not eligible for surgery
  • one course of pre-operative treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age
  • treatment is to be initiated and supervised by a physician experienced in the diagnosis and treatment of uterine fibroids

Please refer to MHRA information prior to initiation.

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6.4.2. Male sex hormones and antagonists

Preferred List
FINASTERIDE (5mg tablets)
Total Formulary
Specialist and GP
DUTASTERIDE

Restrictions: Restricted to specialist initiation.

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CYPROTERONE
Specialist and GP
TESTOSTERONE

Restrictions:

All testosterone preparations are restricted to specialist initiation.  In addition, testosterone transdermal gel is restricted to use on the recommendation of consultant endocrinologists, urologists and oncologists for patients requiring a transdermal delivery system.

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6.4.3. Anabolic steroids

Total Formulary
Specialist Only
NANDROLONE DECANOATE

Restrictions: Restricted to specialist use only.

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