6.3.1. Replacement therapy
Used in adrenocortical insufficiency and occasionally is used for the unlicensed indication of postural hypotension.
6.3.2. Glucocorticoid therapy
Uses include suppression of inflammatory and allergic disorders, cerebral oedema associated with malignancy, croup and chemotherapy-induced nausea and vomiting.
For Formulary advice relating to dexamethasone intravitreal implant, see section 11.4.1
Dexamethasone 40mg tablets (Neofordex®) are not recommended for use in NHS Scotland and are non-Formulary
- Used in adrenocortical insufficiency, shock and hypersensitivity reactions.
- Exludes hydrocortisone modified-release tablets (Plenadren®) which is not recommended for use by the SMC and is non-Formulary.
Restrictions: Excludes 25mg tablets
Used in many inflammatory and allergic disorders.
Restrictions: The treatment of autoimmune hepatitis it is restricted to specialist initiation in non-cirrhotic patients who are intolerant of conventional oral steroids (prednisolone) with severe corticosteroid-related side effects (actual or anticipated) such as psychosis, poorly controlled diabetes or osteoporosis.