6.5.2. Posterior pituitary hormones and antagonists
Restrictions:
Desmopressin tablets are restricted to use in patients unable to use intramuscular preparations. Intravenous desmopressin is restricted to use in specialist haemophilia centres.
Prescribing Notes:
- Used for treatment of diabetes insipidus, primary nocturnal enuresis and postoperative polyuria or polydipsia. Due to the high level of adverse reactions, desmopressin nasal spray is no longer indicated for primary nocturnal enuresis. Oral formulations should be considered as an alternative.
- For use in the symtomatic treatment of nocturia due to idiopathic nocturnal polyuria see section 7.4.2
Restrictions:
Restricted to specialist use to slow the progression of cyst development and renal insufficiency of autosomal dominant polycystic kidney disease (ADPKD) in adults with chronic kidney disease stage 1 to 3 at initiation of treatment with evidence of rapidly progressing disease.
Prescribing Notes:
Prescribing and associated monitoring of this medicine is to be carried out within the acute sector.
Use of tolvaptan for the treatment of SIADH is not recommended for use in NHSScotland by the SMC and is non-Formulary.