Greater Glasgow and Clyde Medicines
Key to symbols The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP The medicine should only be used and prescribed by a specialist Indicates the preferred choice within a class or group of medicines
The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP
The medicine should only be used and prescribed by a specialist
Indicates the preferred choice within a class or group of medicines
4.2. Drugs used in psychoses and related disorders

4.2.2. Antipsychotic depot injections

When considering a first-line choice of long-acting injectable antipsychotic, a first-generation depot medicine should be chosen from the NHSGGC Formulary. The exception to this is where there is good evidence of effect with a specific second-generation antipsychotic (SGA) oral medication favouring its use as an LAI and where compliance, concordance, adherence or persistence with the oral medication is problematic. A second-line choice in the event of treatment failure or emergent, intolerable side-effects with the first-line choice would be an alternative first-generation depot medicine. Again, the exception to this is if there are emergent side-effects including EPSEs or Tardive Dyskinesia, where formulary SGA LAI would be considered.

For further information, see the NHSGGC depot (LAI) algorithm.

Total Formulary
Specialist Only
ARIPIPRAZOLE (Long-acting injection)

Restrictions:

Use for the maintenance treatment of schizophrenia in adult patients stabilised with oral aripiprazole is restricted to use under the overall supervision of a psychiatrist.

Prescribing Notes:

The 1-monthly long-acting injection is now available generically and is the formulary option in NHSGGC.

The 2-monthly long-acting injections (720mg and 960mg) remain currently branded as Abilify Maintena and are non-formulary in NHSGGC.

For further information, see the NHSGGC depot (LAI) algorithm.

BNF Link

Specialist and GP
FLUPENTIXOL DECANOATE

Restrictions:

Restricted to specialist initiation only.

Prescribing Notes:

For further information, see the NHSGGC depot (LAI) algorithm.

BNF Link

Specialist and GP
HALOPERIDOL DECANOATE (Haldol Decanoate)

Restrictions:

Restricted to specialist initiation only.

Prescribing Notes:

For further information, see the NHSGGC depot (LAI) algorithm.

BNF Link

Specialist Only
PALIPERIDONE PALMITATE (injection)

Restrictions:

See Prescribing Notes for further details.

Prescribing Notes:

Formulary indication:

  • The maintenance treatment of schizophrenia in adult patients stabilised with paliperidone or risperidone is restricted to use under the overall supervision of a psychiatrist. The preferred formulation in NHSGGC is the monthly injection as per NHSGGC mental health services LAI Algorithm.

        For relevant SMC advice on Xeplion® click here.

Trevicta® and Byannli® are non-formulary.

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Specialist and GP
ZUCLOPENTHIXOL DECANOATE (Clopixol)

Restrictions:

Restricted to specialist initiation only.

Prescribing Notes:

For further information, see the NHSGGC depot (LAI) algorithm.

BNF Link