Greater Glasgow and Clyde Medicines
Key to symbols The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP The medicine should only be used and prescribed by a specialist Indicates the preferred choice within a class or group of medicines
The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP
The medicine should only be used and prescribed by a specialist
Indicates the preferred choice within a class or group of medicines
2. Cardiovascular system

2.10. Stable angina, acute coronary syndromes and fibrinolysis

2.10.1. Management of stable angina and acute coronary syndromes

2.10.2. Fibrinolytic drugs

Total Formulary
Specialist Only
ALTEPLASE (injection, infusion)

Restrictions:

The fibrinolytic treatment of acute ischaemic stroke is restricted to specialist centres with adequate resources and appropriate expertise and in accordance with detailed protocols. The thrombolytic treatment of occluded central venous access devices including those used for haemodialysisis restricted to second line use after urokinase.

Prescribing Notes:

It should be noted that different alteplase preparations have different licensed indications

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Specialist Only
STREPTOKINASE

Restrictions:

Restricted to specialist use only.

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Specialist Only
TENECTEPLASE (METALYSE)

Restrictions:

Restricted to specialist use only.

Prescribing Notes:

25mg (5000 units) vials used by stroke specialists for the thrombolytic treatment of acute ischaemic stroke in adults within 4.5 hours from last known well and after exclusion of intracranial haemorrhage, as per GGC clinical protocol (in development).

50mg (10 000 units) vials used for acute myocardial infarction.

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