Greater Glasgow and Clyde Medicines

Key Medicine Shortages – August 2022

Monthly Update

  1. Insulin isophane biphasic human 50/50 (Insuman® Comb 50) 100units/ml suspension for injection 3ml cartridge – these have been discontinued with stocks being exhausted imminently. Humalog® Mix 50 remains available, as do other biphasic insulin preparations, and the manufacturers can support a full uplift in supply.

    Please refer to the Medicine Supply Notification on StaffNet for further information and actions required for prescribers.

  2. Remifentanil 1mg, 2mg and 5mg injection – there is a supply problem which may be ongoing for many months. Limited stocks are available and there is a need to prioritise use of remaining stock.

    Please refer to the NHSGGC Medicines Information Memorandum on StaffNet for further information and prescribing recommendations.

  3. Semaglutide (Ozempic®) 0.25mg solution for injection – the manufacturer is unable to advise on when supplies will return to normal. Currently, the 0.5mg weekly and 1mg weekly strengths of semaglutide remain available.

    Please refer to the NHSGGC Central Prescribing Memorandum on StaffNet for background and prescriber information.


Why do medicine shortages occur?
Medicine shortages occur for a variety of reasons, including difficulties sourcing raw materials, product recalls for safety reasons, changes to licence holder, and changes to pack sizes.
It is vitally important that medicine shortages are monitored and appropriate actions taken, to minimise impact on patient care.


Where can I find further advice and information on medicine supply problems and shortages?
For the most up-to-date advice and information please refer to Current Medicine Supply Problems and Shortages page on StaffNet.

Published 22/08/2022. Medicines Update blogs are correct at the time of publication.