Greater Glasgow and Clyde Medicines
Key to symbols The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP The medicine should only be used and prescribed by a specialist Indicates the preferred choice within a class or group of medicines
The medicine should be initiated by, or on the advice of a specialist, but is suitable for continuation by a GP
The medicine should only be used and prescribed by a specialist
Indicates the preferred choice within a class or group of medicines
7.5. Drugs used in Chronic Kidney Disease

7.5.5. Treatment of Primary Immunoglobulin A Nephropathy

Total Formulary
Specialist Only
BUDESONIDE (KINPEYGO)

Restrictions:

Restricted to specialist use in adults with primary immunoglobulin A nephropathy (IgAN) with a urine protein excretion ≥1.0 g/day (or urine protein-to-creatinine ratio ≥0.8 g/g*).
*equivalent to ≥90 mg/mmol

BNF Link

Specialist Only
SPARSENTAN (FILSPARI)

Restrictions:

Restricted to specialist use in adults with primary immunoglobulin A nephropathy (IgAN) with a urine protein excretion ≥1.0 g/day (or urine protein-to-creatinine ratio ≥0.75 g/g*).
*equivalent to ≥85 mg/mmol

Further restricted to patients whose condition has not responded adequately to current standard of care that is; maximally tolerated angiotensin converting enzyme inhibitor or angiotensin receptor blocker and sodium-glucose cotransporter-2 inhibitor, as appropriate. Patients should stop sparsentan at week 24 if no response to treatment.

BNF Link