5.1.7. Some other antibacterials
Restrictions:
Restricted to specialist initiation where nebulised colistimethate is not tolerated and tobramycin is being considered.
Restrictions:
For restrictions please see prescribing notes below
Prescribing Notes:
- Restricted to specialist initiation. Restricted to use on microbiological and infectious disease physician advice only.
Restrictions:
Restricted to use on the advice of local microbiologists and infectious disease specialists only in the following situations:
- in accordance with OPAT service clinical management pathway for second-line use or when meticillin-resistant Staphylococcus aureus (MRSA) infection is suspected AND when the patient is initially hospitalised due to ABSSSI, requires intravenous antibiotics, but is eligible for early discharge as soon as their medical condition does not require further inpatient treatment.
Prescribing Notes:
Please note: this is a PROTECTED ANTIBIOTIC (see policy here) and relevant paper work should be completed.
Restrictions:
Restricted to specialist initiation by a microbiologist or specialist in infectious diseases. Restricted to use in patients not responding to or intolerant of a glycopeptide, or those with microbiological cultures which indicate glycopeptide resistance.
Prescribing Notes:
Please note, this is a PROTECTED ANTIBIOTIC (see policy here) and relevant paper work should be completed.
For daptomycin dosing in adults click here
Restrictions:
Restricted to use only on the advice of a microbiologist or infectious disease physician for multi-resistant organisms.
Prescribing Notes:
Please note: the IV FORM of fosfomycin is a PROTECTED ANTIBIOTIC (see policy here) and relevant paperwork should be completed.
Restrictions:
Restricted to specialist use only. Restricted to hospital-based use on the advice of a microbiologist or infectious disease physician. Prolonged use (>2 weeks) must be avoided.
Prescribing Notes:
Access Linezolid treatment protocol and discharge & outpatient checklist by clicking the hyperlinks.
Please note: this is a PROTECTED ANTIBIOTIC (see policy here) and relevant paperwork should be completed.
Restrictions:
Restricted to use on the advice of local microbiologists and infectious disease specialists only in the following situation:
- in accordance with OPAT service clinical management pathway for second-line use or when meticillin-resistant Staphylococcus aureus (MRSA) infection is suspected AND when the patient is initially hospitalised due to ABSSSI, requires intravenous antibiotics, but is eligible for early discharge as soon as their medical condition does not require further inpatient treatment.
Prescribing Notes:
Please note: this is a PROTECTED ANTIBIOTIC (see policy here) and relevant paper work should be completed.
Restrictions:
Restricted to use only on the advice of microbiologists and specialists in infectious diseases for use in patients with ABSSSI caused by Gram-positive Staphylococcus aureus (specifically methicillin-resistant Staphylococcus aureus [MRSA] isolates) as an alternative oxazolidinone antibacterial.
Please note: this is a PROTECTED ANTIBIOTIC (see policy here) and relevant paper work should be completed.
Restrictions:
Restricted to specialist initiation. Restricted to use on microbiological and infectious disease physician advice only. Vancomycin is the first line glycopeptide.
Restrictions:
Restricted to specialist initiation. Restricted to use on microbiological and infectious disease physician advice only. Vancomycin is the first line glycopeptide.

