Greater Glasgow and Clyde Medicines

Restrictions:

Restricted to use in accordance with regional protocols (see prescribing notes for Formulary indications).

Prescribing Notes:

Erlotinib is Formulary in accordance with the restrictions above for the following indications:

• First-line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with EGFR activating mutations (West of Scotland protocol available here)
• Locally advanced or metastatic NSCLC after failure of at least one prior chemotherapy regimen except in patients who do NOT have an activating EGFR mutation (West of Scotland protocol available here)

Erlotinib is not recommended (and non-Formulary) for the following indications:

• Monotherapy for maintenance treatment in patients with locally advanced or metastatic NSCLC with stable disease after 4 cycles of standard platinum-based first-line chemotherapy
• in combination with gemcitabine for the treatment of metastatic pancreatic cancer

BNF Link