NHS Greater Glasgow & Clyde Area Drug and Therapeutics Committee
Greater Glasgow and Clyde Medicines
Medicines Update

New lipid lowering medicines: Alirocumab and evolocumab

Two new lipid lowering medicines, alirocumab and evolocumab (PCSK9 inhibitors) are on the GGC Formulary for initiation by specialist lipid clinics. Use is restricted to patients with uncontrolled hypercholesterolaemia in accordance with the local protocol (available via StaffNet here). A brief summary of key prescribing information for GPs has been published (on the GGC Medicines website here). Prescribing decisions, including monitoring and adjustment, will be taken by Consultant Medical Biochemists at specialist lipid clinics. 

Use in other patient groups is subject to ongoing discussion. All requests for these medicines are to come from lipid clinics.